Perelman School of Medicine at the University of Pennsylvania
Location: Philadelphia, Pennsylvania
Required Education: MD
Academic / Research
Internal Number: UPEN-672
The Department of Pathology and Laboratory Medicine at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for a Fellowship position in the Academic Support Staff. This appointment will be for one (1) year.
This is a training position for an aspiring pathologist in the rapidly expanding field of cellular therapy. The candidate will work at the campuses of both the Hospital of the University of Pennsylvania (HUP) and the Children's Hospital of Philadelphia (CHOP), with three current Good Manufacturing Practice (cGMP) facilities: the Clinical Cell and Vaccine Production Facility (CVPF) at Penn, the Cell and Gene Therapy Laboratory (CGTL) and the Clinical Vector Core (CVC) both at CHOP. The cellular therapy activities at HUP and CHOP cover the entire range of standard-of-care adult and pediatric bone marrow transplant, from collection to processing to infusion. The cGMP facilities also engage in a large number clinical trials under Investigational New Drug or Device Exemptions (IND/IDEs) approved by the FDA, some of which are in collaboration with third party industrial sponsors. Examples of these IND/IDEs include the manufacturing of Chimeric Antigen Receptor T cells, virus specific cytotoxic T lymphocytes, and selective T/B cell depleted transplant grafts. The candidate will have a wide exposure of different cGMP labs all within walking distance, learn the set up and operation of cGMP facilities, in addition to the actual manufacturing processes.
Cellular therapy is a highly regulated field. The candidate will also engage in managing different quality aspects of cell manufacturing, participate in drafting IND/IDE Chemistry, Manufacturing and Controls (CMC) sections, including response to FDA inquiries. There are numerous opportunities for quality improvement projects. Didactic training, either one-on-one with a faculty or part of more formal course, is also available. The candidate is encouraged to tailor the one-year program to suit individual background and needs, while still gaining enough exposure to become proficient in all areas. Ideally, a successful candidate would leave the program feeling confident to direct a cell therapy facility.
Applicants must have an M.D. or M.D./Ph.D. or equivalent degree and have demonstrated excellent qualifications in education, research, and clinical care. Candidates must be Board Certified/Board eligible in Anatomic Pathology (AP), Clinical Pathology (CP) or AP/CP. Documents needed: Curriculum Vitae; Personal Statement; three potential references.
Inquiries: Yongping Wang, MD, PhD Director, Cell and Gene Therapy Lab Children's Hospital of Philadelphia Dept of Pathology and Lab Medicine
We seek candidates who embrace and reflect diversity in the broadest sense. The University of Pennsylvania is an EOE. Minorities/women/individuals with disabilities/protected veterans are encouraged to apply. The University of Pennsylvania values diversity and seeks talented students, faculty and staff from diverse backgrounds. The University of Pennsylvania is an equal opportunity and affirmative action employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status or any other legally protected class. Questions or concerns about this should be directed to the Executive Director of the Office of Affirmative Action and Equal Opportunity Programs, University of Pennsylvania, 421 Franklin Building, 3451 Walnut Street, Philadelphia, PA 19104-6205; or (215) 898-6993 (Voice) or (215) 898-7803 (TDD).
About Perelman School of Medicine at the University of Pennsylvania
The Perelman School of Medicine is recognized worldwide for its superior education and training of the next generation of physician-scientists and future leaders of academic medicine. With a top five ranking from US News and World Report, the nation's oldest medical school is indeed one of its best.
Penn emphasizes intellectual achievement and compassion in our three missions of patient care, education, and research. Our students are among the finest in the nation. They are matched in quality by the high level of instruction and research that we offer. Penn ranks second in the country in research and training grants awarded to medical schools by the National Institutes of Health. Our research strengths encompass all basic science and clinical disciplines and contribute to a rich and vibrant intellectual environment that generates wide-ranging innovation and advancement in medical care.